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No. 4.

THE LONDON SCHOOL OF TROPICAL MEDICINE to COLONIAL OFFICE.

(Received 12th December, 1921.)

SIB,

Seamen's Hospital, Greenwich, S.E.10, 9th December, 1921.

I HAVE the honour to submit for the consideration of the Advisory Committee for the Tropical Diseases Research Fund the reports of the following Special Departments in the School :-

Entomology, by Professor A. Alcock, C.I.E., F.R.S. Helminthology, by Professor R. T. Leiper, D.Sc., F.Z.S. Protozoology, by Dr. J. Gordon Thomson.

The School is now settled in its new quarters in Endsleigh Gardens, and the work of the establishment, including the three Special Departments on behalf of which the Tropical Diseases Research Fund is good enough to make a grant, is making very satisfactory progress.

The enclosed reports tell in detail of the work that has been accomplished. It is hoped within the near future that we may be able to submit a full statement in regard to the Expedition to British Guiana conducted by Professor Leiper and his colleagues.

Dr. E. W. O'Connor, Assistant Entomologist, whose absence in the Western Facific was mentioned in a previous communication, has just returned to London, and his preliminary report is submitted herewith. The School have now arranged for Dr. O'Connor to devote the next few months to preparing a complete statement of his research in the Western Pacific, a copy of which will also be forwarded for the information of the Advisory Committee of the Tropical Diseases Research Fund.

I am, &c.,

P. J. MICHELLI,

SIR,

Enclosure 1 in No. 4.

Secretary.

REPORT OF THE Director of the Department of Medical ENTOMOLOGY, LONDON SCHOOL OF TROPICAL MEDICINE.

I HAVE the honour to submit the following report on this Department of the School for the half-year ending 31st October, 1921.

1 have been in charge of the Department all the time. The Assistant in the Department, Dr. F. W. O'Connor, has been in Samoa, in charge of the expedition for the study of Filariasis in the Pacific Islands, which left England in October, 1919; on the 31st October he was on his way back to England. During the period under report, Lieut.-Colonel H. T. Walton, I.M.S., lately Professor of Pathology and Parasitology at the Lucknow Medical College, has rendered good assistance in the Department.

With the assistance of Colonel Walton, I have conducted two ordinary School courses of fifty-six hours each in Medical Entomology, and two of three hours each (supplemented by special demonstrations) on the Than A tophidia and their venoms; also a special course of Medical Entomology, of forty-five hours, for special students. Among those attending the last named course was the Sanitary Commissioner of 'Assam.

During the summer and autumn I resumed my observations-so far as suitable hospital-cases of malaria provided opportunity on the phenomena of malaria- infection in the common British anopheline mosquito, Anopheles maculipennis, partly under conditions approximating to nature, and, partly under controlled conditions. Though the weather was abnormally hot it was also abnormally dry, and under these conditions it was practically impossible to bring about infection of the insects, even when they were provided with cases, of malaria harbouring gametocytes in great plenty: under those conditions, however, the malaria-parasite appeared to make abortive attempts of some persistence to develop in the insect.

By the kindness of Colonel S. P. James, I.M.S., of the Ministry of Health, I was able to visit the Isle of Grain in the summer, and there to collect specimens of Anopheles maculipennis from a house where two children convalescent from

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(indigenous) malaria were domiciled: not one of the insects, however, was found afterwards to be infected. When Colonel Walton and I visited the Isle of Grain, in October, Anopheles maculipennis was very hard to discover as a result of the prolonged summer drought.

By the courtesy of the Air Ministry, this Department of the School has been accorded a footing at the Halton Air Camp in Buckinghamshire a locality very favourable for the study of medical entomology. For this most desirable hospitality we are indebted particularly to Air-Commodore M. H. G. Fell, C.B., C.M.G., Air-Commodore F. R. Scarlett, D.S.O., and Wing-Commander H. M. S. Turner, M.B.E.

The additions to the teaching collections include the following:--Anopheles from Siam, Dr. M. E. Barnes; Venomous fishes from Palestine, Dr. P. Buxton: Papataci midges from the Punjab, Lieut.-Colonel Clifford Gill, I.M.S.; Anopheles from Malaya, Dr. W. A. Lamborn; Papataci midges from the Punjab frontier, Major J. A. Sinton, V.C., I.M.S.; Mosquitoes and Cordylobia from Zanzibar, W. M. Aders; Stegomyia fasciata eggs from Nigeria, Dr. and Mrs. Connal; Glossina from West Africa, Dr. J. Dalrymple; Diptera of many kinds from the Sudan, Dr. R. T. Stones; Anopheles and other miscellanea from Honduras and Jamaica, Major W. F. M. Loughman, M.C.,. R.A.M.C.; Anopheles from Trinidad, Dr. Lennox Pawan.

Also there has been presented, locally, by Major J. E. M. Boyd, M.C., R.A.M.C., larvæ and cocoons of Ceratophyllus; by Dr. G. H. Dart several lots of ectoparasites; and by Miss Rhoda Jones, living sheep-reds.

SIR,

I have, &c.,

A. ALCOCK, LIEUT.-COLONEL, I.M.S. (Retired), Professor of Medical Zoology in the University of London; Director of the Department of Medical Entomology,

London School of Tropical Medicine.

Enclosure 2 in No. 4.

REPORT OF DIRECTOR OF HELMINTHOLOGY.

I HAVE the honour to present a report on the work of my Department for the year ending 31st October, 1921.

Teaching. Three courses of lectures and laboratory instruction in Helmin. thology were given during the year as part of the general curriculum of the School: The teaching during the winter session was conducted by me;

that during the spring

and summer sessions by Dr. G. M. Vevers. Five students joined the laboratory for special work in systematic Helminthology, viz. M. Khalil, M.D. (Egypt), A. J. Hesse, M.A. (South Africa), R. J. Ortlepp, M.A. (Natal), F. Ware, M.R.C.V.S. (India), Miss H. Matthews, B.Sc., C. T. Maitland, B.Sc., D.P.H. (England); also a considerable number of visitors, notably Professor Yoshida, of Osaka University, spent brief periods in the laboratory examining the collections and preparations.

Throughout the winter of 1920-1921, I continued to act as Director of the Research Laboratory of the Zoological Gardens, thus securing opportunities for members of the Department to examine the animals dying in the Gardens for entosoal parasites. Advantage was taken of this arrangement for routine field work by Dr. Vevers (who acted during that period as honorary Parasitologist), Mr. A. J. Hesse, Dr. Khalil and Mr. Ortlepp (who later succeeded Dr. Vevers officially there).

The work of the Department has been greatly extended during the period under review by aid of grants from the Medical Research Council, the Ministry of Agriculture, and the British Medical Association. Under these outside grants C. U. Lee, M.B., F. E. Philpot, M.Sc., T. Goodey, D.Sc., M. Turner, M.Sc., and J. Markbreiter, B.Sc., were attached to the Department as Research Assistants. Mrs. Williams continued, as during the previous year, to give honorary services for special bibliographical work.

Research Expedition.-In February, 1921, the School Committee appointed me in charge of an expedition to British Guiana and the West Indies to inquire into certain problems associated with filarial diseases; in this Dr. Vevers, Dr. Khalil, and Dr. Lee took part. Dr. J. Anderson was also appointed for this Research with

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