M 127

An effort has been made, and is being continued, to find any relationship between the incidence of Nephritis and a previous history of malarial infection.

Nephritis:-

(a) Acute—co-existing with Subtertian Malaria...... 2 cases

(b) Sub-acute 3 cases

(One case co-existing with Quartan Malaria)

(c) Chronic Parenchymatous Nephritis 8 cases

(d) Chronic Interstitial Nephritis 3 cases

One associated with Arterial Hypertension.

One associated with Cerebral Haemorrhage.

The results of the urea concentration test in nephritic cases associated with malaria show a definite impairment of renal function. Results in other cases would seem to suggest that a condition of so-called nephrosis is present. They suffer from oedema, urine contains much albumen, and a few hyaline casts and renal function tests give satisfactory results. There is no evidence of cardiovascular disturbances.

Neurological Cases:-

Neurological cases have been fully investigated. Lumbar puncture with full examination of Cerebro-spinal fluid and measurement of its pressure has been performed in all cases.

Respiratory Diseases :-

As regards Respiratory Diseases the operation of Pneumo-thorax has been done in only a very small number of cases because it is extremely difficult to get suitable early types of Pulmonary Tuberculosis.

Intra-tracheal injections of lipiodol have been made with a view to demonstrating the nature of the lung lesions in some cases.

Arterial Hypertension:-

There is a high incidence of this condition amongst the Chinese and special treatment has been and is being used in this state. Continued trial of Angioxyl, a pancreatic extract, and of Hypotensyl, a combination of extract and Gypsine from mistletoe, also of Padutin are being made.

Ascites:-

Many of these cases have an obscure etiology and efforts have been made to further our knowledge of the causation by removing samples of the ascitic fluid and estimating the Sodium Chloride content by means of the Conductivity Method and also by Smirk's chemical method. I am greatly indebted to Mr. E. R. Dovey, Chief Government Analyst, for his help in this direction.

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