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In view of the varying cocaire content of the coca leaf in Afferent countries, and in different harvests in the same country, this proportion must bo based not only on the quantity of oooa leaf but also on its cocaine sontent.

Care will have to be taken that notwithstanding the restrictive me asures which may be tekoa in the cultivation of the coca loaf

for the world market remains sufficiently profitable for prądustion

to be maintained, Moreover, should cultivation be limited to certain countries, measures will have to be considered for ensuring a sufficient supply for the medical reeds of the different countries

in time of war.

It is generally egroed that the quantity of 300sine at present available is much too large for the medical and scientific needs of the whole world. Nevertheless, greet prudence will have to he oxercised in imposing restrictions, so as to permit of que

e cnsideration of various consequences of restriation.

Prudence

is especially necessaly inasmuch as tho ezgot figures of production and of the quantitics rcquired for medical purposes are not known.

Measures will bure to be dcvised to prevent illicit trado from getting hold of the cocaine intended for medical uso, end to ensure that it will always be possible to obtain orcaine

It will therefore for legitimate purposes at a reasonable price.

be pocossery to make provision for the possibility of a bad crop, and for an increase in the legitimate needs of eastern countries, in which the employment of European remedios is constantly becoming

more frequent,

It should not be forgotten that a proportional restriction of cultivation in the various countries would not produce the desired result, firsly, because an extensivo cultivation is nooded in Peru for internal consupti x1, and, secondly, because the yield does not depend solely on the area under cultivation, tut also on

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