$12 should not obtain.

24. 512 there is no doubt, on the other hand, about the occasional existence of intestinal plague in man, specially in severe epidemics. Such lesions in the human subject resemble those found in the rodent. Peyer's patches are swollen with contained or surrounding haemorrhagic infiltrations. Ulcerations are usually present and the ileum, in general, covered with petechiae, swollen, and congested. Buboes are often found in the mesentery, of considerable size with the haemorrhage extending widely from all sides.

In conclusion, these experiments, coupled with the results of Professor Klein, and the recent investigations of the Indian Plague Commissioners, establish the fact, hitherto disputed, that by feeding rodents, e.g. Guinea rats, etc., with plague tissues or cultures of the B. pestis, plague infection, of various types, can be induced, and that by such methods of experimentation, the existence of intestinal plague is placed beyond dispute.

William Hunter.

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