person affected with it. But this power of infection appears to depend greatly on the state of health, and surrounding conditions of the recipient. That is to say, it is greatly facilitated by the recipient living in a filthy and smelling home, under insanitary conditions, and also by his low state of health resulting from bad food, uncleanly habits, etc. Whether the poison is present in the dejecta, and can be conveyed in food or water is still sub judice. It would appear likely that it can be carried in the clothes of those with the disease. Both males and females affected suffer alike, the majority of cases occurring in young adult life.

After an incubation period of about 4 or 5 days (in one case it would appear shorter), the disease is ushered in with rigors, headache, sometimes vomiting and general feeling of malaise, high fever rapidly supervenes, the temperature going to about 104° and remaining raised, without much remission in cases which end in death. In cases which appear to be recovering, the temperature has come down by lysis in two or three days. In the severest forms, the temperature has reached 105° and 106°, and in a few cases death has occurred within 24 hours of invasion.

Glandular swelling makes its appearance early, affecting the groin, femoral region, armpits, neck, or other space. These buboes are painful to the touch, inflamed, and tender. In a few cases they have gone on to suppuration, and I have opened them when they were red and tender to the touch.

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