.
180
Post-mortem Examination. There was no pathological lesion to indicate the cause of death, and nothing was found microscopically or bacteriologically.
Experiment No. III.
Animal-One pig.
Preliminary observations, the same as before.
October 7th, 1904.-To-day the pig was fed with a spleen and blood obtained from a recently dead case of Beri-beri (acute). The post-mortem examination was performed, within two hours after death, and the heart blood and spleen mashed and mixed with boiled rice.
October 8th, 1904.-Pig lively, no diarrhea, slight loss of appetite, and apathy. It scarcely ever moves in its pen preferring to lie sleeping in a corner of the enclosure.
October 15th, 1904. The animal has kept well, the appetite has returned, and it moves in a normal fashion. There has been no rise in temperature since the commencement of the experimental.- Vide Chart.
October 16th, 1904.-Fed again to-day with a large amount of mashed Beri- beri organs. The liver, spleen, stomach and duodenum, heart and kidneys with blood of an extremely acute and cdeniatous case of Beri-beri were obtained one hour after death. These were sliced into small pieces, mixed with the blood and boiled rice, and placed before the animal. The pig made a hearty meal finishing every particle placed before him.
October 17th, 1904.-To-day the animal is dull and apathetic and refuses to move from a corner of its pen. During the day it has had severe vomiting and diarrhoea. The former consisted of undigested pieces of the tissues eaten. The latter was composed of loose bile-stained fæces which apart from their fluidity were normal. The animal is able to locomote normally and has no recognisable epi- gastric tenderness.
October 18th, 1904.--The pig was again fed with post-mortem tissues, namely, the internal organs of the pig used for Experiment No. IV. (q.v.). These the animal devoured heartily.
October 20th, 1904.-The temperature has commenced to rise (r. Chart) and from this day onwards the fever followed a course similar to that observed under Experiment No. I. The total duration of this fever was 7 days. During this time the pig became much reduced in weight and ate but little food. There was never any diarrhoea, and the animal locomoted and functioned exactly as other pigs. There was no cedema or recognisable epigastric tenderness.
October 27th, 1904.-From this date onwards the temperature became normal and never again went above 102° F. It is unnecessary therefore to continue the fever chart at greater length. The animal was much thinner but in the course of a few days commenced to recover its normal condition.
Continued observation of the animal was kept up for the following five months, during which time nothing abnormal was noted. The temperature con- tinued normal, the appetite was good. There was no diarrhoea, no epigastric tenderness, and no trace of general or local adema. The motor and sensory apparatus of the animal appeared at all times to be perfectly normal.
At the present time, a year after the commencement of the experiment, the pig is as healthy and fat as any pig could be.
Experiment No. IV.
Animal-One pig.
Preliminary observations, as before.