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Post-mortem Examination.-The skin and subcutaneous tissues were markedly congested. The pericardium contained a small quantity of blood-stained watery fluid. The parietal layer was normal. The visceral coat showed the presence of numerous minute blood extravasations. These were most pronounced along the tracts of the coronary vessels. The heart was normal. Nothing abnormal was found in the trachea or lungs. Several of the meliastinal glands were deeply hæmorrhagic, the majority, however, only showed enlargement, slight congestion and serous infiltration. The liver and gall bladder were normal. The latter was distended with thick, glairy, tenacious bile. The rumen, reticulum and oma- sum were normal.
The abomasum was acutely inflamed, more particularly towards its upper end. Minute and irregularly shaped hæmorrhagic foci were found scattered throughout the surface of the mucous membrane. Ulceration was just commencing. There was no marked necrosis. Spreading over the whole extent of the mucous membrane, was a delicate film of greyish, and easily detachable exudate. The duodenum was inflamed but not ulcerated. The changes in the small intestine resembled those met with in the abomasum. It was acutely inflamed and ulceration and necrosis were on the point of commencing. The cæcum was very much congested. Hæmorrhagic extravasations were diffusely scattered over the entire mucous surface. These varied in number and size, being most numerous and of greatest extent towards the cæcal or blind end.
The ileo-cæcal valve was normal. In the vicinity immediately around the valve ulceration was marked.
The large intestine was generally inflamed. Hæmorrhagic foci were scattered throughout its entire length, ulceration and necrosis were just on the point of beginning. The rectum was in a similar condition. The spleen was normal,
The mesenteric lymphatic glands were enlarged and congested. Many were deeply pigmented; a few, however, were deeply hæmorrhagic. The kidneys were healthy.
The urinary bladder was inflamed, sinal hæmorrhages were found in the mucous membrane. The animal was pregnant. The foetus was about 3 months old. The uterus and appendages were normal. A post-mortem examination was made on the fœtus but nothing pathological was detected. The peripheral lymphatic system of the animal was distinctly pathological. Both parotid glands were normal. The right submaxillary gland was also normal but that on the left side was deeply hæmorrhagic. The prescapular lymphatic glands were enlarged and congested and contained an excessive amount of serous or mucoid like fluid, right precrural lymphatic gland was enlarged and congested-that on the left side was deeply hæmorrhagic. The inguinal lymphatic glands were deeply congested and infiltrated with mucoid fluid. The iliac lymphatic glands were deeply hæmorrhagic.
The
Blood films, smears from different organs and cultures, were made and the bacillus demonstrated microscopically and obtained in pure culture.
HEIFER CALF "D".
For two days prior to experimentation the animal was under observation. The temperature was taken morning and evening and found to vary between 101.5° F. and 102.5° F. To all appearance the animal was in perfect health. On the afternoon of the third day the animal was fed with an emulsion of blood, spleen and lymphatic gland. In all about one pint of this emulsion was given. The in- fective material from which the emulsion was prepared was obtained from Ox No. 145, as in the case of Bullock "A." For 3 days after the experiment no obvious change was observed in the condition of the animal. On the 4th day, feeding was again resorted to, a pint of blood being obtained from Ox No. 176, vide post-mor- tem chart No. 31. In this ox, the disease had run a typical course.
On the 3rd October, 1903, a decided reaction was inanifest, the temperature in the evening reaching 105,2° F. The animal still remained to all appearance healthy. On the following day occasional rigors were noticeable. The animal con- tinued to take its usual quantity of food and water up until the 6th of October, when it left the half of its ration untouched and greedily drank more than its usual allowance of water, On the next day all food was refused, rumination was sus pended, the belly was "tucked up," the back arched, and the head and ears hung listlessly. The coat began to sture and a scurfy condition of the skin was noticeable over the withers and rump.
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