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thin, greyish yellow character with streaks of mucus and traces of blool. In one or two instances distinct solid masses were found. These presented the appear- ance of casts of the gut. They were extremely friable, greyish yellow in colour and were non-adherent to the mucous membrane of the bowel.
The ileo-cæcal valve may be normal. In many cases congestion, hæmorrhages, ulceration and necrosis are met with. The character of these changes is identical with that of the abomasum. The cæcun and large intestine are also involved in changes similar to those found in the abomasum, although the degree of such changes is less. Congestion and submucous hemorrhages are frequent, but the occurrence of ulceration and necrosis is somewhat rare. In the large intestine, along the crests of the longitudinal rugæ congestion, inflammation and hemorrhages occur. These give the mucous surface of bowel a peculiar streaked or striped appearance. Such a condition is frequently found extending throughout the whole of the large intestine.
The contents of the cæcum and large intestine resemble those found in the small intestine. The rectum presents an appearance akin to that found in the large intestine. The anus is frequently excoriated.
The liver is as a rule unchanged. Fatty infiltration is fairly common. Jaundice is also met with. In one case insular hæmorrhages were found scattered in the parenchyma. Chronic biliary cirrhosis caused by the presence of the Distoma Hepaticum in the bile ducts was frequently met with. This condition has probably nothing to do with the disease as it is daily met with among healthy animals in the slaughter-house.
In the majority of cases the gall bladder was found to contain a thick glairy bile.
In many
cases this had distended the organ to twice its normal size. The mucous membrane was often found congested and inflamed. In other cases necrosis and ulceration were present in addition. Hæmorrhages and petechire were occasionally found.
The spleen was found unaltered in the majority of instances. Congestion and enlargement may be present. In other cases infarctions and hæmorrhages are found in its substance. Rarely the spleen may be even diminished in size.
Genito-Urinary Organs.—The kidneys are usually normal to the naked eye. The pelvis and ureters are also healthy. The bladder, however, may show con- gestion with submucous hæmorrhagic extravasations, No ulceration or necrosis have been found.
The majority of animals examined were males. From the small number of females examined, it is scarcely possible to make any general statement with regard to the effects of this disease upon the female generative organs. However ulceration of the vagina appears to be fairly common. One case of pyometra was examined, but the significance of this condition in relation to the disease in question was unde- termined.
The Lymphatic System.-A constant feature of the disease is the condition of the lymphatic glands. In every instance of the disease so far met with the lymphatic glands throughout the whole body were the seat of marked changes, these consisting of extensive hæmorrhagic extravasation into their substance, congestion with enlargement, and frequently the presence of a large amount of infiltration, The peri-lymphatic connective tissue was usually the seat of serous infiltration. Exact details in regard to the condition of the individual lymphatic glands in each case is given in the Appendix on post-mortem examinations.
serous
WILLIAM HUNTER. ADAM GIBSON.
Appendix D.
BACTERIOLOGY OF THE DISEASE.
After a careful analysis of the symptoms and pathological appearances present- ed by this disease, it becomes evident to the investigator that there is no limit as to the extent of the morbid process in the body. of an affected animal. The changes met with are certainly most pronounced and most frequently found in some struc- tures, e.g., the lymphatic glands, the abomasum, etc., but they are not necessarily