CONFIDENTIAL ##

Subject

15. Narcotics

Buprenorphine Clinical Trial

Purpose

To conduct clinical trials on buprenorphine, a possible non- addictive substitute for methadone.

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Progress Made and Present Position

a) The final protocol was approved by the

Supervisory Committee on 27 October 1982.

b) Finance Committee deferred approval of funds on 27 October 1982 and asked for more information on specific points.

Next Quarter's Target

a) To clarify the points raised by the Finance Committee and obtain its approval of funds.

b) To commence phase I

mini-trial when financial approval is obtained.

GF 323

CONFIDENTIAL #B

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