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[REMARKS: There is always the possibility that monkeys, or even any animal, are not susceptible to Beri-beri. WRIGHT's experiments were positive, ours negative. Given WRIGHT's experiments as positive, then in all probability there are no micro-organisms in the blood of Beri-beri cases.]
Experiment No. III.
Animal-One monkey.
Nature of experiment:-
This was carried out in the same way as the previous two experiments. The usual preliminary observations were made and precautionary measures were taken.
October 8th, 1904.-The monkey received 10 c.c, blood from a moribund case of acute Beri-beri.
October 20th, 1904.-10 c.c. of blood injected from another case of œdeinatous Beri-beri, in the morning.
October 20th, 1904.-In the afternoon 8 c.c. blood injected.
October 25th, 1904.-4 c.e blood injected.
October 28th, 1904.-8 e.c. blood injected.
Total amount injected, 40 c.c. blood.
(Vide temperature chart).
Nothing found in the blood microscopically or bacteriologically.
No ill health of animal, no paralyses, sensory or motor, no epigastric tenderness.
From November, 1904, to October, 1905, the animal has remained in perfect health.
Experiment No. IV.
Animal-One monkey.
Nature of experiment:--
This was carried out in a similar fashion to the three
preceding experiments.
(Vide temperature charts).
Five different inoculations of blood from different cases of Beri-beri were made.
Total quantity of blood injected—30 c.c.
The
no
The blood of animal was negative microscopically and bacteriologically. animal was never ill there was no paralysis: no epigastric tenderness: oedema. It was alive and well 9 months after the beginning of the experiment and presented no signs of Beri-beri.
Experiment No. V.
Animal-One monkey.
Nature of experiment:-
This was performed as in the preceding experiments. The usual precautionary measures were taken. The cases of Beri-beri from which the blood was taken were acute and oedematous and atrophic.
Four different inoculations at different periods were performed. In all the animal received subcutaneously 45 c.c. of human Beri-beri blood.
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