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RIA IN CLINICAL APPLICATIONS
Its
Radioimmunoassay (RIA for short) is a micro-diagnostic
method for external diagnosis developed in the 1960's. emergence has in an all-round way innovated the clinical diagnostic technology, fully demonstrating the pioneering feature of nuclear medicine. By now, RIA has been widely applied
in many basic and clinical medical fields, such as molecular
biology, physiology, endocrinology, ontology, hematology,
materia medica, gynaecology and obstetrics, and eugenics.
RIA Basic Principle and Characteristics
RIA, in the final analysis, is but an application of
isotopic dilution in its new form.
RIA is built on the basis of the competitive combination
on the part of the antigens to be tested and the identical
antigens already marked by tracer atoms with the limited amount
of specific antibodies. The number of the marked antigens being
combined is in a negative correlation with the number of antigens.
to be tested. And with the help of a specification curve, it
is possible to quantitatively analyze the content of antigens
to be tested.
Based on the similar principles, various ultra-micro
analytical methods can be built, such as competitive protein
P. 1
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