M 119
B. Cholera.
In this instance, the routine treatment adopted consisted of giving patients a hypodermic injection of 1/100 of a grain of atropine sulphate on admission, intravenous infusions of three pints of normal saline and of a two per centum solution of sodium bicarbonate as often as necessary, drinks of Kaolin emulsion during the acute stage to the extent tolerated by the patient and a pill containing three grains of potassium permanganate hourly until the clinical symptoms had disappeared.
Careful attention was paid to the temperature of the patient before and during the actual time of the infusion and the temperature of the solution varied accordingly.
As a rough guide the following rule was followed :—
Rectal temperature of patient. Temperature of infusion. 95° 102 104°F. 97°F. 98 T 99°F. 97 100°F. 94 www 95°F. 100 102°F. 102 or over. Unwarmed at room temperature.At the suggestion of the dean of the London School of Hygiene and Tropical Medicine—based on certain research work carried out on animals at the School—"streptocide" was exhibited in a series of fifty unselected cases with fifty controls in addition to the usual routine treatment outlined above. Two grammes of "streptocide" were given to alternate cases on admission followed by one gramme four hourly for four days.
The mortality rates for both series showed no variation of any statistical significance. The number, of course, was too small and the experiment will be repeated.
H. F. TAI,
Chinese Medical Officer in charge Infectious Diseases Hospital.
Appendix VI.
CLINICAL INVESTIGATIONS ON SOME AETIOLOGICAL FACTORS OF BERI-BERI.
I. AGE, OCCUPATION AND SEX INCIDENCE OF BERI-BERI PATIENTS.
(a) Age. (b) Sex. Under 1 year Nil. Male Female From 2 to 5 Nil. 799 207 From 6 to 15 21 From 16 to 30 507 From 31 to 60 446 61 and over 32 Total 1,006 Total 1,006M 119
B. Cholera.
In this instance, the routine treatment adopted consisted of giving patients a hypodermic injection of 1/100 of a grain of atropine sulphate on admission, intravenous infusions of three pints of normal saline and of a two per centum solution of sodium bicarbonate as often as necessary, drinks of Kaolin emulsion during the acute stage to the extent tolerated by the patient and a pill containing three grains of potassium permanganate hourly until the clinical symptoms had disappeared.
Careful attention was paid to the temperature of the patient before and during the actual time of the infusion and the temperature of the solution varied accordingly.
As a rough guide the following rule was followed :—
Rectal temperature of patient.
95°
97°F.
97
100°F.
100
102°F.
Table II.
Temperature of infusion.
102 104°F.
98
T
99°F.
94
www
95°F.
102 or over.
Unwarmed at room temperature.
At the suggestion of the dean of the London School of Hygiene and Tropical Medicine-based on certain research work carried out on animals at the School- "streptocide" was exhibited in a series of fifty unselected cases with fifty controls in addition to the usual routine treatment outlined above. Two grammes of "streptocide" were given to alternate cases on admission followed by one gramme four hourly for four days.
The mortality rates for both series showed no variation of any statistical significance. The number, of course, was too small and the experiment will be repeated.
H. F. TAI,
Chinese Medical Officer in charge Infectious Diseases Hospital.
Appendix VI.
CLINICAL INVESTIGATIONS ON SOME AETIOLOGICAL FACTORS OF
BERI-BERI.
I. AGE, OCCUPATION AND SEX INCIDENCE OF BERI-BERI PATIENTS.
Table I.
(a) Age.
(b) Sex.
Under 1 year
Nil.
From 2 to 5
Nil.
From 6 to 15
21
From 16 to 30
507
Male Female
799
207
From 31 to 60
446
61 and over
32
Total .........1,006
Total...1,006
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