AnnualReport-1935 — Page 484

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(3) Library. The following books were added to the library during the year:---

1. A Text Book of Histology, E. V. Cowdry, 1935.

2. Applied Physiology, Samson Wright, 1934.

3. Laboratory Diagnosis, Todd and Sandford, 1934.

(4) Research. (a) Typhoid fever. Results obtained in the routine use of clot culture in parallel with agglutination for enteric fever are again of sufficient interest to warrant comment. The figures for the year are as follows:—

Widal positive culture positive 87 " negative 222 negative " positive 9 " " doubtful 7 " " negative 726 Total sera tested 1,100 325 19 49 Widal negative culture positive 71

Analysis reveals the fact that of the total of positive cases (325) no less than 16 or 4.92% were either negative or doubtful by agglutination but gave a growth on culture. This compares with 3.50% in 1934. Quite apart from this aspect of the case is the usefulness of the procedure as a check on the sensitivity and accuracy of the Widal by the use of the percentage quoted as a comparative standard. This percentage should (all other things being equal) not vary greatly from year to year. The routine use of the procedure would appear to be thoroughly warranted.

(b) Dysentery. Strains of Flexner dysentery organisms have been typed regularly during the year following the work begun in 1932, and during the past two years 128 strains have been studied. These fall into the following groups.

Total of whole study 1935 V 12% 9.5% W 31% 29.5% X 17% 15.0% Y 2% 4.5% Z 0 1.0% ZX 14% 21.0% Mixed 11% 10.0% Inagglutinable 13% 9.5%

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(3) Library. The following books were added to the library during the year:--- 1. A Text Book of Histology, E. V. Cowdry, 1935. 2. Applied Physiology, Samson Wright, 1934. 3. Laboratory Diagnosis, Todd and Sandford, 1934. (4) Research. (a) Typhoid fever. Results obtained in the routine use of clot culture in parallel with agglutination for enteric fever are again of sufficient interest to warrant comment. The figures for the year are as follows:— Widal positive culture positive 87 " negative 222 negative " positive 9 " " doubtful 7 " " negative 726 Total sera tested 1,100 325 19 49 Widal negative culture positive 71 Analysis reveals the fact that of the total of positive cases (325) no less than 16 or 4.92% were either negative or doubtful by agglutination but gave a growth on culture. This compares with 3.50% in 1934. Quite apart from this aspect of the case is the usefulness of the procedure as a check on the sensitivity and accuracy of the Widal by the use of the percentage quoted as a comparative standard. This percentage should (all other things being equal) not vary greatly from year to year. The routine use of the procedure would appear to be thoroughly warranted. (b) Dysentery. Strains of Flexner dysentery organisms have been typed regularly during the year following the work begun in 1932, and during the past two years 128 strains have been studied. These fall into the following groups. Total of whole study 1935 V 12% 9.5% W 31% 29.5% X 17% 15.0% Y 2% 4.5% Z 0 1.0% ZX 14% 21.0% Mixed 11% 10.0% Inagglutinable 13% 9.5%

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- M 111 (3) Library. The following books were added to the library during the year:--- 1. A Text Book of Histology, E. V. Cowdry, 1935. 2. Applied Physiology, Samson Wright, 1934. 3. Laboratory Diagnosis, Todd and Sandford, 1934. · (4) Research. (a) Typhoid fever. Results obtained in the routine use of clot culture in parallel with agglutination for enteric fever are again of sufficient interest to warrant comment. The figures for the year are as follows:—- Widal positive culture positive 87 J? 71 " negative. 222 325 negative "" positive 9 doubtful 7 }} >> 19 " negative...... 49 negative J 726 Total sera tested .1,100 Analysis reveals the fact that of the total of positive cases (325) no less than 16 or 4.92% were either negative or doubtful by agglutination but gave a growth on culture. This compares with 3.50% in 1934. Quite apart from this aspect of the case is the usefulness of the procedure as a check on the sensitivity and accuracy of the Widal by the use of the percentage quoted as a comparative standard. This percentage should (all other things being equal) not vary greatly from year to year. The routine use of the procedure would appear to be thoroughly warranted. (b) Dysentery.-Strains of Flexner dysentery organisms have been typed regularly during the year following the work begun in 1932, and during the past two years 128 strains have been studied. These fall into the following groups. Total of whole study. 1935. V. 12% 9.5% W. .31% .29.5% X. .17% .15.0% Y. 2% 4.5% Z. 0 1.0% ZX .14% .21.0% Mixed .11% 10.0% Inagglutinable .13% 9.5% }

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- M 111

(3) Library. The following books were added to the library during the year:---

1. A Text Book of Histology, E. V. Cowdry, 1935.

2. Applied Physiology, Samson Wright, 1934.

3. Laboratory Diagnosis, Todd and Sandford, 1934.

Widal positive culture positive

negative.

222

325

negative

positive

doubtful

}}

negative......

negative

726

Total sera tested

.1,100

(b) Dysentery.-Strains of Flexner dysentery organisms have been typed regularly during the year following the work begun in 1932, and during the past two years 128 strains have been studied. These fall into the following groups.

Total of whole study.

1935.

12%

9.5%

.31%

.29.5%

.17%

.15.0%

4.5%

1.0%

.14%

.21.0%

Mixed

.11%

10.0%

Inagglutinable

.13%

9.5%

}

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