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special reference to clinical and bacteriological questions. It is not expected that this inquiry will be completed before the end of the year, and it is not possible at the present time to indicate the scientific results.

I gladly take this early opportunity, however, of expressing the deep gratitude of the Commission to His Excellency, Sir Wilfrid Collett, K.C.M.G., Governor of British Guiana, C. Clementi, Esq., C.M.G., the officer administering the Colony during the greater part of our stay, and officers of the various departments of the Government who assisted our work in every way.

The investigations were carried out in the closest co-operation with the Medical Department, and we have to record our appreciation of the valuable help received from Dr. A. T. Ozzard and Dr. Boase, Acting Surgeon-Generals Dr. E. P. Minett, Government Medical Officer of Health, and Dr. F. G. Rose, head of the Government Bacteriological Laboratory. Dr. Craigen, the Colonial Surgeon, and prior to his return from leave, Dr. MacQuaide, afforded us the full facilities of the Government Hospital.

Daring somewhat brief visits to Barbados, Dr. Anderson and I were much indebted to Dr. Hutson for the opportunities he gave us of a rapid survey of the sanitary conditions of the Island. At Antigua- a brief study was made of the conditions which are favourable there to the spread of intestinal bharziosis. Here Dr. Branch and Mr. A. E. Collens, of the Agricultural Department, gave valuable aid and information.

Publications. During the year, fifteen papers have been prepared for publica- tion by members of the Staff or workers in the Department. The following is a list of titles. Owing to absence abroad several of these papers still await publication: those published are indicated by an asterisk.

Medical:-

1. The present incidence of hookworm infection in the Cornish Tin Mines.

By Professor R. T. Leiper, M. Khalil, M.D., and F. E. Philpot, M.Sc.

2. Thermotropism in Ankylostome larvæ. By M. Khalil, M.D., D.P.H,

3. Observations on the action of Tartar emetic on the eggs and miracidia of

Bilharzia Hæmatobia. By M. Khalil, M.D.

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4.

5.

6.

7.

On Bilharzia infection in the New World. By M. Khalil, M.D., and C. U. Lee, M.B.

On the incidence of Filaria infection in Alberttown, Georgetown. By

M. Khalil, M.D.

On the septic tank in the Tropics from a Helminthological standpoint.

By M. Khalil, M.D.

On the incidence of Filaria infection amongst Chinese, East. Indians, Portuguese, Blacks, and Mixed races in Georgetown. By C. U. Lee, M.B.

*8. On some developmental stages of Ancylostoma ceylanicum Looss, 1911.

By G. M. Vevers, M.R.C.S.

Agricultural:-

9. Experiments on the development of Syngamus trachealis in the chick.

By M. Turner, M.Sc.-

10. On Heterakis vesicularis of Poultry and its larval development. By

M. Turner, M.Sc.

11. Results of Routine Examination of English Fowls for helminth Parasites.

By M. Turner, M.Sc.

*12. On the susceptibility of Clover and some other Legumes to Stem-disease caused by the eelworm Tylenchus dipsaci syn, densatatrix Kuhn. By T. Goodey, D.Sc.

13. Notes on the behaviour of the ensheathed larvæ of Graphidium strigosum

and Trichostrongylus retortæformis. By T. Goodey, D.Sc.

General:-

14. Some members of the family Dicrocoelidæ affecting domestic animals.

By F. Ware, M.R.C.V.S.

15. A short description of the genitalia of Ancistrocephalus polypteri Leydig.

1853. By A. J. Hesse, M.A.

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Probably the most important observation made during the year is that described He has by Dr. Khalil in his paper on "Thermotropism in Ankylostome larvæ.' discovered that hookworm larvæ are not only highly stimulated by rising tempera- tures, but are definitely attracted towards the source of heat. This gives a new and satisfactory explanation of the invasion of the skin by hookworm larvæ. It is

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possible that this reaction may prove a useful biological test to differentiate larvæ of all nematode species which enter their hosts through the skin.

I have to report with much regret the loss of Miss Turner, who resigned at the end of September to proceed to India.

At the West Indian Medical Conference, held in British Guiana in June and July, 1921, I had the privilege of representing, with Dr. Anderson, the London School of Tropical Medicine, and, in September, I attended, as a guest of the Rockefeller Foundation, the Conference held on the occasion of the ceremonial dedication of the Union Medical College in Peking.

While visiting Trinidad, I had the pleasure of meeting Dr. W. W. Cort, who was there in charge of a Research expedition started on similar lines to our own. This Mission had been sent out from the John Hopkins University for four months' work, and was being subsidized by the Rockefeller Foundation. It was gratifying to learn that the new School of Hygiene in Baltimore attaches great importance to this mission, and that similar expeditions are being planned by them for next year.

I have, &c.,

R. T. LEIPER,

Enclosure 3 in No. 4.

REPORT BY J. G. TROMSON, M.A., M.B., Ch.B., DIRECTOR OF PROTOZOOLOGY, FOR THE HALF-Year ending 30TH NOVEMBER, 1921. DURING the period in question, the following students have received instruc- tion, or have performed research work, in Protozoology:-

1. As part of the general course to qualify for the examination for the D.T.M. and H. (London).

Summer Term Autumn Term

2. Advanced students in Protozoology:

Summer Term Autumn Term

74 .56

130

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This includes four candidates for the degree of B.Sc. (honours) in Zoology who

are taking Protozoology, as Protozoology is the special subject. In the case of one

of these students the examination is being conducted at present.

3. Advanced student and research worker-Dr. L. H. Booth, Colonial Service,

is studying a series of blood films from children brought by him from the West Coast of Africa.

4. Scholarships awarded to Department of Protozoology.-Dr. Robertson, Assistant in Protozoology, has been awarded a Grocers' Research Scholarship. The following researches have been carried out in the Department :- Drs. J. G. Thomson and Andrew Robertson have investigated the fæces of amoebic dysentery cases, and have emphasized the value of Charcot-Leyden crystals in diagnosis. Their findings have been published in the Transactions of the Royal Society of Medicine (Tropical Section), under the title of

"The Value of Laboratory Reports on Stools in Cases of suspected Amoebic Dysentery, and their Interpretation by the Clinician; with a special note on the Diagnostic Significance of Charcot-Leyden Crystals."

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A further paper by the same authors is in the press at the present moment, viz. : Charcot-Leyden Crystals in the Stools as an Aid to the Diagnosis of Entamoebic Dysentery."

Experimental work has been done on T. cruzi, and on the reduvid Rhodnius prolixus, the carrier of the trypanosome in Venezuela. In a demonstration before the Royal Society of Tropical Medicine various preparations of the trypanosome, the bug and its eggs; were shown by Drs. Thomson and Robertson. Mr. H. E. Hornby, O.B.E., F.R.C.V.S., D.V.S.M., while working in the Department, published a paper entitled

"Trypanosomes and Trypanosomiases of Cattle." in the Journal of Comparatire Pathology and Therapeutics.