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PUBLIC RECORD OFFICE

Reference:

wmmm miCO.885/25

PUBLIC RECORD OFFICE, LONDON

ALLY WITHOUT PERMISSION OF THE BE REPRODUCED PHOTOGRAPHIC- COPYRIGHT PHOTOGRAPH-NOT TO

Publications :---

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1. R. Newstead, F.R.S. On the genus Phlebotomus, III. Bulletin of Entomological Research, Vol. VII., pages 191, 192, figure 1, a-c (1918). 2. R. Newstead, F.R.S.-Observations on Scale Insects (Coccida), III.

Bulletin of Entomological Research, Vol. VII., pages 343-380, figures 1-27, plates VI., VII. (1917).

3. R. Newstead, F.R.S.-Observations on Scale Insects (Coccida), IV. Bulletin of Entomological Research, Vol. VIII, pages 1-34, figures 1-22 (1917). Copies of the above publications are submitted, but they are not intended for publication.

I have, &c.,

ROBERT NEWSTEAD,

The Secretary,

SIR,

Professor of Entomology.

Incorporated Liverpool School of Tropical Medicine,

B10, Exchange Buildings, Liverpool.

Enclosure 3 in No. 14.

The Incorporated Liverpool School of Tropical Medicine,

B10, Exchange Buildings, Liverpool, 30th November, 1917.

I HAVE to submit the following report on work done in the Department of Parasitology during the period 1st November, 1916, to 31st October, 1917.

Tuition. The number of students attending the course of instruction for the Diploma of Tropical Medicine was seven in the autumn term, 1916, two in the Lent term, and seven in the autumn term, 1917. Ten veterinary students were given the customary instruction in parasitology.

By arrangement with the War Office special courses of instruction in tropical parasitology were arranged for Medical Officers proceeding to the East. Three special courses, which were given gratuitously by the staff of the School, were each of a fortnight's duration. During the past six months three such classes have been held and have been attended by about seventy Medical Officers. As many of these officers have testified their great appreciation of these short courses it is hoped to continue them from time to time during the future.

War Work. This has again figured prominently during the past year, and is concerned mainly with two diseases, dysentery and malaria.

Malaria.--Details of the work done in this disease are given in the report of the Professor of Tropical Medicine.

Dysentery-The Department has undertaken the protozoological examination of the fæces of dysenterics in the military hospitals of the Liverpool district; this work, which has been undertaken by Miss Mackinnon (lent for a time by the War Office), Messrs. H. F. Carter, J. R. Matthews, and Malins Smith, has been of an onerous nature, and has involved no less than some 9,000 microscopic examinations of some 1,700 cases. As a result of this routine work much valuable information has been obtained.

Coincidently with the work on the fæces of dysenterics, many examinations have been made of the stools of non-dysenterics, including those of a large number of individuals, young recruits and civilians, who have never been out of England. These observations have revealed the interesting and important fact that a propor- tion (about 35 per cent.) of persons who have never been out of England and who give no history of having suffered at any time from dysentery, pass in their stools Cysts which are in all respects (both as regards morphology and pathogenicity identical with the cysts of Entamoeba histolytica found in the fæces of chronic and convalescent dysenterics.

A series of papers dealing with this research have been published during the past twelve months; references are appended at the end of this report.

Dr. Blacklock and I have conducted an investigation devised with the object of throwing some light on the remarkable phenomenon of nocturnal periodicity in the cutaneous vessels of Microfilaria bancrofti. The results of our work have been published in the paper quoted below.

Dr. J. W. W. Scott Macfie and I have examined the morphology of the Spirochaetes responsible for European, African, and Indian relapsing fevers, and have reached the conclusion that there is at present no means of distinguishing these parasites morphologically.

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Some months ago I was asked by the Veterinary Officer in charge of a large veterinary hospital attached to a remount depôt in the neighbourhood of Liver- pool to identify certain parasitic worms causing a heavy mortality amongst the horses which were recently imported from America. I have asked Dr. Macfie to join me, and, so far as time allows, we are engaged in this task. A rough survey showed the parasites to belong for the most part to various genera of the family Strongylidæ. Sclerostomum equinum, S. edentatum, and S. vulgare were found in many of the horses, also several species of the genus Triodentophorus and many In several of species of Cylichnostomum, including some hitherto undescribed. the horses large numbers of the small nematode Probstmayria vivipara were present. The work of identification is, however, far from complete, and, as the material is very abundant and the time which we can at present devote to the subject very limited, it will be some time before our report will be ready for publication.

The following is a list of papers published during the last twelve months :---

1. Smith, A. Malins, and Matthews, J R.-The Intestinal Protozoa of Non- dysenteric Cases. Annals of Tropical Medicine and Parasitology, Vol. X., No. 4, pages 361-390.

2. Carter, Henry F-Remarks on the Spirochetes occurring in the Fæces of Dysenteric Patients. Annals of Tropical Medicine and Parasitology, Vol. X., No. 4, pages 391-396.

3. Stephens, J. W. W., and Mackinnon, Doris L.-A Preliminary State- ment on the Treatment of Entamba histolytica Infections by "Alcresta ipecac." Annals of Tropical Medicine and Parasitology, Vol. X, No. 4, pages 397-410.

4. Carter, Henry F., Mackinnon, Doris L., Matthews, J. R., and Smith, A. Malins. The Protozoal Findings in Nine Hundred and Ten Cases of Dysentery Examined at the Liverpool School of Tropical Medicine from May to September, 1916 (First Report). Annals of Tropical Medicine and Parasitology. Vol. X., No. 4, pages 411-426.

5. Carter, Henry F., Mackinnon, Doris L., Matthews, J. R., and Smith, A.

Malins. Part V., with Stephens, Lieutenant-Colonel J. W. W.- Protozoological Investigation of Cases of Dysentery conducted at the Liverpool School of Tropical Medicine (Second Report). Annals of Tropical Medicine and Parasitology, Vol. XI., No. 1, pages 27-68. 6. Yorke, Warrington, and Blacklock, B.--The Occurrence of Ankylostoma ceylanicum in West African dogs. Annals of Tropical Medicine and Parasitology, Vol. XI., No. 1, pages 69-74.

Macfie, J. W. S., and Carter, H. F.-The Occurrence of Spirocheta eurygyrata in Europeans in England, with a Note on a second species of Spirochæta from the Human Intestine. Annals of Tropical Medicine and Parasitology, Vol. XI., No. 1, pages 75-80.

8. Macfie, J. W. S., and Yorke, Warrington-The Relapsing Fever Spiro- chates. Annals of Tropical Medicine and Parasitology, Vol. XI., pages 81-86.

9. Yorke, Warrington, Carter, Henry F., Mackinnon, Doris L., Matthews, J. R., Smith, A. Malins.-Persons who have never been out of Great Britain as Carriers of Entamoeba histolytica. Annals of Tropical Medicine and Parasitology. Vol. XI, No. 1, pages 87-90.

10. Yorke, Warrington, and Blacklock, B.--Observations on the periodicity of Microfilaria nocturna. Annals of Tropical Medicine and Parasitology, Vol. XI., No. 2, pages 127-148.

11. Smith, A. Malins, and Matthews, J. R.-Further Records of the occurrence of Intestinal Protozoa in Non-dysenteric Cases. Annals of Tropical Medicine and Parasitology. Vol. XI., No. 2, pages 183-194.

12. Carter, Henry F., and Matthews, J. R.-The Value of Concentrating the Cysts of Protozoal Parasites in examining the Stools of Dysenteric Patients for Pathogenic Entamoeba. Annals of Tropical Medicine and Parasitology, Vol. XI., No. 2, pages 195-204.

I have, &c.,

The Secretary,

Warrington YORKE, Professor of Parasitology.

Incorporated Liverpool School of Tropical Medicine,

B10, Exchange Buildings, Liverpool.

c2

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